Ipamorelin is a synthetic pentapeptide and a highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHS-R1a). It belongs to the Growth Hormone Releasing Peptide (GHRP) class but is distinct for its specificity. Unlike earlier generations (such as GHRP-6 or GHRP-2), Ipamorelin is designed to stimulate growth hormone release without significant stimulation of ACTH (cortisol) or prolactin, making it a primary candidate for highly specific endocrine research.
Ipamorelin mimics the action of ghrelin by binding to the GHS-R1a receptor in the anterior pituitary. This binding initiates a signal transduction pathway involving phospholipase C and IP3, leading to the release of growth hormone vesicles. Research highlights its "selectivity profile," focusing on its ability to elevate plasma GH levels while maintaining baseline levels of cortisol and prolactin, thereby isolating the somatotropic effects from the stress response axis.
This product is sold for in-vitro laboratory research purposes only. It is not a drug, food, or cosmetic and is not intended for human or veterinary consumption. All handling should be performed by qualified professionals in a controlled laboratory setting. Forge Peptides is not liable for any misuse of this product. By purchasing, you agree that you are a qualified researcher or a scientific professional.
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