Cagrilintide is a novel, long-acting acylated analogue of the endogenous hormone amylin (islet amyloid polypeptide). Structurally, it acts as a non-selective agonist for both the amylin (AMY) and calcitonin gene-related peptide (CGRP) receptors. It is frequently utilised in "combination" research protocols alongside GLP-1 agonists to observe synergistic effects on metabolic parameters.
Cagrilintide permeates the blood-brain barrier to target specific nuclei within the central nervous system, particularly the area postrema. Investigation focuses on its ability to modulate satiety signalling pathways and regulate gastric emptying rates independent of the incretin system. Current studies are examining the synergistic potential of co-administering amylin analogues with GLP-1 receptor agonists to enhance weight modulation efficacy in metabolic models.
This product is sold for in-vitro laboratory research purposes only. It is not a drug, food, or cosmetic and is not intended for human or veterinary consumption. All handling should be performed by qualified professionals in a controlled laboratory setting. Forge Peptides is not liable for any misuse of this product. By purchasing, you agree that you are a qualified researcher or a scientific professional.
